In this chapter we present exact Quantum Monte Carlo results of the ground-state energy and structure of a Bose gas confined in highly anisotropic harmonic traps. Starting from a 3D Hamiltonian, where interparticle interactions are model by a hard-sphere or a soft-sphere potential, we show that the system exhibits striking features due to particle correlations. By reducing the anisotropy parameter , while the number of particles and the ratio of scattering to transverse oscillator length are kept fixed, the system crosses from a regime where mean-field theory applies to a regime which is well described by the 1D Lieb-Liniger equation of state in local density approximation. In the cross-over region both theories fail and one must resort to exact methods to account properly for both finite size effects and residual 3D effects. For very small values of we find clear evidence, both in the energy per particle and in the longitudinal size of the cloud, of the fermionization of the system in the Tonks-Girardeau regime.